Get the best outcomes from our expression systems, including the GS Gene Expression System® technology platform and the XS technologies® microbial expression system. We support you with practical guidance to diagnose issues, select the right optimization levers, and accelerate progress from early expression into process-ready performance.
You can engage us for:- Onboarding and best-practice use of our expression technologies
- Structured optimization plans
- Troubleshooting based on your data and your platform configuration
- Scale-up considerations and alignment to manufacturability goals
We provide dedicated GS Gene Expression System® platform support to help you fully leverage the platform for monoclonal antibodies and next-generation biologics. Support is centered on using the platform effectively, from design choices through to stable expression and scale-up readiness.
If you’re adopting the GS system® technology platform for the first time, or looking to improve outcomes in an established workflow, our experts help you reach stable, scalable performance faster.
Read more about GS system® platform or speak to our expert.
We support you to maximise performance using Lonza’s XS Technologies® microbial expression platform, including the XS® Pichia expression system and XS® E.coli expression system.
We support customers with:
- Selecting the right XS® microbial platform host approach based on molecule requirements
- Improving expression/secretion performance using XS® platform best practices
- Increasing consistency and scalability through structured optimization
Support is tailored to the way the XS Technologies® microbial expression platform is designed to be used, helping you reach a fit-for-purpose microbial expression route faster.
Read more about XS technologies® platform or speak to our expert.
Receive focused support to apply Lonza’s proprietary technologies and production know-how for cell and gene therapy programmes. Our experts support viral vector expression and early production development with guidance designed to improve yield, robustness, and scalability.
Support may include:
- Practical guidance on upstream process parameters and critical decision points
- Troubleshooting performance variability and prioritizing optimization actions
- Preparing development processes for stepwise scale-up and manufacturability
Our support connects early viral vector development decisions with downstream processing and GMP manufacturing expectations helping you progress with greater confidence.
Read more about Viral Vector Production or speak to our technical expert.
Ask the Experts in Expression
Lonza provides technical guidance to help developers apply the GS Gene Expression System® technology platform according to established platform principles. Support includes assistance with vector and host selection, expression workflow setup, evaluation of process parameters, and review of data to identify suitable optimization approaches. Our team also helps ensure alignment between early development decisions and later process requirements. You can reach our specialists through the “Speak to a GS system® platform expert” contact option on the technical support page.
Our team helps investigate areas that commonly influence expression outcomes, such as clone behaviour, vector configuration, media and feed strategies, and transitions between expression formats. We review user-generated data to identify potential contributing factors and outline practical steps that fit within the GS® platform framework. This approach supports consistent evaluation and informed decision making without implying performance guarantees.
XS Technologies® microbial expression platform optimization covers host selection aligned to molecule characteristics, assessment of expression or secretion behaviour, and guidance on establishing a reliable microbial workflow. Support follows the intended use of the XS® Pichia and XS® E. coli systems and focuses on identifying suitable development paths. To begin, we typically request information such as construct design, early expression data, and any known process constraints so we can provide tailored, non comparative technical recommendations.
Yes. We offer technical support for applying Lonza’s viral vector tools during early development. Guidance may include reviewing parameters such as cell density, feed strategies, and transduction conditions. Our team helps identify potential sources of variability and outlines practical considerations for establishing processes suited to future scale up and manufacturing needs. This support is intended to inform development decisions without suggesting performance improvements relative to other technologies or service providers.
Technical support is adapted to the needs of each modality and stage of development. Early stage guidance often focuses on expression strategy, host or vector selection, and establishing a workable process foundation. As programs progress, support may include considerations for scaleup, process consistency, regulatory alignment, and manufacturing suitability. The intent is to help developers apply Lonza technologies appropriately throughout their development pathway, without implying comparative advantages over alternatives.
Sign up. Stay up-to-date.